Information for healthcare professionals

Efficacy


High-precision, highly effective radiotherapy

Brachytherapy is an effective treatment option that is used worldwide to treat a wide range of cancers.

Brachytherapy is a standard of care in the treatment of cervical cancer and is widely used to treat prostate cancer.

Brachytherapy’s precision targeting of radiation to the treatment site enables high radiation doses to be delivered to a highly defined area. This precision allows clinicians to achieve a high level of dose conformity – i.e. ensuring the tumor receives an optimal radiation dose. It also reduces the risk of radiation damage to healthy tissues, organs and structures around the tumor. These features make brachytherapy a highly effective treatment modality for many types of cancers.

brachytherapy

Small or locally advanced tumors

Brachytherapy can be used to treat cases of small or locally advanced tumors, with the aim of curing the cancer (provided the cancer has not metastasized).

  • Brachytherapy often offers a comparable approach to surgery for primary tumors, achieving the same probability of cure, with similar or reduced side effects.1,2
  • Brachytherapy can be used either as monotherapy, or in combination with other approaches such as surgery or external beam radiotherapy (EBRT).


Advanced disease

In advanced disease stages, brachytherapy can be used for effective palliative treatment, providing symptom relief from pain and bleeding.

  • If the tumor is not easily accessible or is too large to ensure an optimal distribution of irradiation to the treatment area, brachytherapy can be combined with other treatments.
  • It is often used in combination with EBRT and/or surgery.
  • Combining these approaches with brachytherapy can further improve patient outcomes, compared with using these approaches on their own.3-5


Brachytherapy efficacy outcomes

Brachytherapy is an important cancer treatment modality in cancer care.

The efficacy of brachytherapy has been demonstrated in the settings of curative, adjuvant, neo-adjuvant and palliative treatment.


Find out about the efficacy outcomes of brachytherapy for specific cancer types:


References
  1. Guedea F, et al. Clin Transl Oncol 2009;11(7):470-8.
  2. Litwin SM, et al. Cancer 2007;109:2239–47.
  3. Viswanathan AN, et al. In Devlin PM (Ed), Brachytherapy: applications and techniques. Philadelphia, PA, LWW. 2007.
  4. Hoskin PJ, Motohashi K, Bownes P, et al. Radiother Oncol 2007;84(2):114–20.
  5. Pieters BR, de Back DZ, Koning CCE, Zwinderman AH. Radiother Oncol 2009;93(2):168–73.
Page last updated on 14 January 2011.

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